Some of the principal characters include:
- Mikhael (Mik) Rasputin, a 25-year-old millionaire artist;
- Harlequinn (Harley) Goldman, his 19-year-old boyfriend, a punk musician in a group named "Boy Band";
- Skids DiAngelo, Harley's friend and bandmate, a happy-go-lucky bisexual 19-year-old college student;
- Cyanide Torres, Harley and Skids' friend and bandmate, a 19-year-old drummer and chemistry major, ostensibly heterosexual but with unresolved feelings for Skids;
- Rasheequa Jackson, law student and feminist activist, and bassistist for the therefore somewhat inaccurately named Boy Band;
- Tabitha Sinclair, Mik and Harley's landlady and daughter of Satan;
- Tybalt O'Donnell, Mik's lascivious ex-boyfriend with designs on Harley and Skids;
- Collin Sri'Vastra, cynical self-proclaimed asexual (though in a relationship with Fox) and enemy of Skids;
- Fox Maharassa, wild and mischievous bisexual, best friend and lover of Collin.
See Queer culture.
- Boy Meets Boy was also the name of a somewhat controversial American television program on the Bravo cable network in the late summer and autumn of 2003.