A buffalo is one of several species of bovine. It includes the Asian genus Bubalus, among which are the water buffalo, the anoa and the tamaraw, and the African genus Syncerus, most famous member of which is the Cape buffalo.

The word buffalo is also often used to denote the American bison.

Buffalo is also the name of some places in the United States of America:

• Buffalo, Iowa
• Buffalo, Kentucky
• Buffalo, Minnesota
• Buffalo, New York
• Buffalo, Texas
• Buffalo, Wisconsin
• Buffalo, Wyoming
• Buffalo Township, Pennsylvania

There is also Buffalo Grove, Illinois.