It is sometimes suggested that the Act was introduced as a measure against the clergy, since the Act was introduced following the separation of the Church of England from Rome, though there seems to be no firm evidence for this. The Act itself only states that there is was no "sufficient and condigne punyshment" for such acts.
Contravention of the Act, along with treason, led Lord Walter Hungerford, 1st Baron Hungerford of Heytesbury, to become the first person executed under the statute in July 1540, though it was probably the treason that cost him his life. Nicholas Udall, a cleric, playwright, and Headmaster of Eton College, was the first to be charged for violation of the Act alone, in 1541. In his case the sentence was commuted to imprisonment, and he was released in less than a year.